Methotrexate vial

Solution for injection 1000mg/10ml, 5000mg/50ml

Methotrexate 100 mg/ml solution for injection may be used for the following indications:

• Acute lymphocytic leukaemias (ALL)
In combination with other cytotoxic medicinal products

• Non-Hodgkin’s lymphomas
In combination with other cytotoxic medicinal products in adult patients with Non-Hodgkin’s lymphomas of intermediate and high degree of malignancy
In combination with other cytotoxic medicinal products in paediatric patients

• Head and neck cancer
As palliative monotherapy in patients with metastatic or recurrent disease

• Breast cancer
In combination with other cytotoxic medicinal products in patients for adjuvant treatment after tumour resection or mastectomy and for palliative treatment in advanced disease

• Choriocarcinoma and similar trophoblastic diseases
As monotherapy in patients with good prognosis (low risk)
In combination with other cytotoxic medicinal products in patients with poor prognosis (high risk)

• Osteosarcoma
In combination with other cytotoxic medicinal products for adjuvant and neoadjuvant therapy

• Cancer of the bladder
In combination with other cytotoxic medicinal products